Can septal myectomy prevent sudden cardiac death in hypertrophic obstructive cardiomyopathy?

نویسندگان

  • Georgios K Efthimiadis
  • Soultana Meditskou
  • Nikolaos E Mezilis
  • Ioannis Styliadis
  • Anastasios Manthos
  • Georgios E Parcharidis
چکیده

in patients with acute coronary syndromes: a collaborative meta-analysis of randomized trials. JAMA 2005;293:2908–2917. 5. Antman EM, Cohen M, Bernink PJ, McCabe CH, Horacek T, Papuchis G, Mautner B, Corbalan R, Radley D, Braunwald E. The TIMI risk score for unstable angina/non-ST-elevation MI: a method for prognostication and therapeutic decision making. JAMA 2000;284:835–842. 6. Yan AT, Yan RT, Tan M, Fung A, Cohen EA, Fitchett DH, Langer A, Goodman SG. Management patterns in relation to risk stratification among patients with non-ST-elevation acute coronary syndromes. Arch Intern Med 2007; 167:1009–1016.

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Hypertrophic obstructive cardiomyopathy: the Mayo Clinic experience.

BACKGROUND Hypertrophic cardiomyopathy (HCM) is a primary myocardial disease characterized by left ventricular hypertrophy in the absence of other etiologies. Clinical presentation may vary from asymptomatic to sudden cardiac death. Medical treatment is the first-line therapy for symptomatic patients. Extended left ventricular septal myectomy is the procedure of choice if medical treatment is u...

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Recent meta-analyses have shown good long-term survival of patients with hypertrophic obstructive cardiomyopathy (HOCM) after alcohol septal ablation (ASA) comparable with surgical myectomy. However, gradient reduction after ASA was slightly less favourable [1, 2] and in a singlecentre study a higher rate of aborted sudden cardiac death was found [3]. The following case report illustrates the i...

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Survival after alcohol septal ablation for obstructive hypertrophic cardiomyopathy.

BACKGROUND The clinical efficacy of alcohol septal ablation for obstructive hypertrophic cardiomyopathy (HCM) has been demonstrated, but the long-term effects of the procedure remain uncertain. This study examined the survival of patients after septal ablation performed in a tertiary HCM referral center. METHODS AND RESULTS We examined 177 patients (mean age, 64 years; 68% women) who underwen...

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Arrhythmia/Electrophysiology Survival After Alcohol Septal Ablation for Obstructive Hypertrophic Cardiomyopathy

Background—The clinical efficacy of alcohol septal ablation for obstructive hypertrophic cardiomyopathy (HCM) has been demonstrated, but the long-term effects of the procedure remain uncertain. This study examined the survival of patients after septal ablation performed in a tertiary HCM referral center. Methods and Results—We examined 177 patients (mean age, 64 years; 68% women) who underwent ...

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Meta-analyses of septal reduction therapies for obstructive hypertrophic cardiomyopathy: comparative rates of overall mortality and sudden cardiac death after treatment.

BACKGROUND Septal reduction for obstructive hypertrophic cardiomyopathy may be performed by surgical myectomy or alcohol septal ablation (ASA). Unlike surgical myectomy, ASA creates an intramyocardial scar that may potentiate the risk of ventricular arrhythmias and sudden cardiac death (SCD). METHODS AND RESULTS Systematic reviews for ASA and surgical myectomy were performed. Study selection ...

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عنوان ژورنال:
  • European heart journal

دوره 28 17  شماره 

صفحات  -

تاریخ انتشار 2007